Tonight's programme will come from the Tory party conference in Manchester, where Jeremy Paxman will be joined by an audience of conference attendees.
Jeremy will be speaking to MPs Philip Hammond, David Davis and Don Foster. Also we'll be getting the journalist's view of the conference from Fraser Nelson and Kevin Maguire.
The main topic for discussion will be the economy and Chancellor George Osborne's big speech today and David Grossman will be giving his analysis of what the chancellor said.
Plus Iain Watson will be looking at the European economic crisis amid the news that Greece is likely to miss targets to cut its budget deficit.
And as the government announces that it is going to invest £50m to commercialise graphene - a carbon allotrope invented at Manchester University - we ask what is it and why is it important?